Genome Editing and Therapeutics - Faculty - Center for Disease Neurogenomics - Manhattan, NY

Faculty recruitment in Genome Editing and Therapeutics at Center for Disease Neurogenomics (CDN) at the Icahn School of Medicine at Mount Sinai in New York City.

We are inviting applications for tenure-track faculty position (Assistant and Associate Professor level) for scientists that are working to develop the next generation of genome editing techniques and RNA and DNA-based therapeutics.

This includes biomedical engineers, bioengineers, developmental biologists and molecular and cellular biologists that apply state-of-the-art approaches for new nucleic acid delivery technologies, such as CRISPR gene and base editing tools and oligonucleotide therapeutics, and approaches for more sophisticated control of transgene expression. We are looking for scientists that apply this emerging technology to human neurons and organoids, with the objective of discovering novel genes critical in neuronal maturation and function, and/or developing multiplexed approaches to evaluate the combinatorial interactions between the hundreds of genetic variants underlying neuropsychiatric disease risk. Next generation human genome editing and forward genetic neuronal screens will allow members of CDN to resolve the interactions

between genetic variants, cell types and molecular functions within an enhanced disease-relevant context.

The Center for Disease Neurogenomics is a hub of neurogenomics and disease biology, towards development and enhancement of precision medicine across neuropsychiatric disorders. The candidate will join anoutstanding team of scientists with world class expertise in a broad range of disciplines, including genetics and genomics, neuroscience and clinical psychiatry. The CDN philosophy is highly geared towards collaboration, inclusion, and cross-disciplinary interactions, particularly between basic wet lab and dry lab scientists and

clinicians, and we provide strong support to junior scientists.

The Center for Disease Neurogenomics is part of the Mount Sinai Health Care System, which is one of largest hospital systems in the United States, and the Icahn School of Medicine, which includes outstanding departments in psychiatry, neuroscience, genetics, immunology, stem cell biology, and experimental therapeutics, and over 5,000 faculty. The highly integrated structure of Mount Sinai's departments, institutes

and clinical divisions provide a unique environment for scientific and medical collaborations that foster an ideal atmosphere for innovations aimed at addressing 21st century biomedical challenges. Mount Sinai is ranked as one of the nation's top biomedical institutions in research, patient care, and education, and over the last 10 years has become a leader in biomedical data science. In addition to the CDN, faculty recruits will be appointed in the Departments of Psychiatry, Genetics and Genomic Sciences and Neuroscience, which are among the top 5 ranked departments in the USA based on NIH funding.

Applicants should hold a Ph.D., M.D. or M.D./Ph.D. and are expected to develop independent research programs. Candidates for the Associate Professor ranks must have a distinguished record of published research, demonstrating significant impact on the profession, and success at securing funding to support research programs. We offer highly competitive recruitment packages, strong institutional commitments to

faculty support, comprehensive benefits, relocation services, and a rewarding work and life environment. The Icahn School of Medicine at Mount Sinai is located in the heart of Manhattan, one block from Central Park.

Compensation range from 165K to 200K (not including bonuses / incentive compensation or benefits).

Salary Disclosure Information:

Mount Sinai Health System provides a salary range to comply with the New York City law on Salary Transparency in Job Advertisements. Actual salaries depend on a variety of factors, including experience, specialties, historical productivity, historical collections, and hospital/community need. As such, an actual salary may fall closer to one or the other end of the range, and in certain circumstances, may wind up being outside of the listed salary range. The salary range listed is for full-time employment and does not include bonuses / incentive compensation or benefits.

Please specify Job Title of interest and send CV with Cover Letter to:

Alex Cano

Executive Director Physician Recruitment

Mount Sinai Health System

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Strength Through Diversity

The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai's unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by:

• Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential.

• Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination.

• Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers.

We work hard to acquire and retain the best people and to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong and are able to professional advance. We share the belief that all employees, regardless of job title or expertise contribute to the patient experience and quality of patient care.

Explore more about this opportunity and how you can help us write a new chapter in our history!

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time -- discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes approximately 7,400 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 14 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism."

EOE Minorities/Women/Disabled/Veterans

Requisition ID : 23000012