Cleveland Clinic • Cleveland, OH 44101
Job #2686935185
Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.
The Charis Eng laboratory is seeking a highly motivated, self-driven postdoctoral research fellow for the Genomic Medicine Institute at Cleveland Clinic Lerner Research Institute. PTEN hamartoma tumor syndrome (PHTS) is molecularly defined as the presence of germline PTEN mutation. Why mutation of a single gene PTEN results in specific cancer risks and/or autism spectrum disorder (ASD) is unknown. The Eng lab seeks modifiers from genome seq which may help bifurcate cancer vs ASD clinical outcomes. The successful candidate will have demonstrated proficiency in bioinformatics, computational genomic epidemiology and/or data science.
This position will be co-advised by Dr. Eng (human genomicist) and Dr, Ni (computational biologist).
Principal Investigator: Charis Eng, MD, PhD; Ying Ni, PhD
Lerner Research Institute Department: Genomic Medicine Institute
Lab Research Topics:
Inherited disorder PTEN hamartoma tumor syndrome (germline PTEN mutation)
Computational genomic epidemiology
Bioinformatics
Omic modifier(s) of germline PTEN mutation
Which bifurcate phenotypes
For more information about the lab's research, please visit: ~~~ or contact Dr. Eng at ~~~ .
Job Responsibilities:
Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
Identification and characterization of modifiers interacting with PTEN mutation
Integrative analysis of multi-omics data for feature selection
Provide clear, detailed and thorough progress reports
Education:
PhD or MD/PhD required
MD with relevant laboratory experience may substitute for PhD
Languages:
Work Experience:
Previous experience in a research or academic setting. Graduate student experience meets this requirement.
Scientific writing experience
Additional Preferred Qualities:
PhD required
Trained and proficient in bioinformatics, data science and or computational genomics
Highly motivated and self-driven individual with exemplary work-ethic and ability to promote team-spirit/collegiality
Physical Requirements:
Ability to perform work in a stationary position for extended periods
Ability to operate a computer and other office equipment
Ability to communicate and exchange accurate information
Ability to distinguish color
Manual dexterity to handle specimens and repair equipment
Ability to lift and transport equipment or specimens weighing up to 20 pounds
May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.
Personal Protective Equipment:
Preferred Application Materials:
CV
Research statement
Three references (names and contacts)
All application materials should be submitted directly via email to Dr. Charis Eng at ~~~ .
Keywords: Postdoc, Research, LRI, Genomic Medicine Institute, Omic modifiers, Germline PTEN mutation
Pay Range
Minimum hourly: $0.01
Maximum hourly: $333,340.26
The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement.
Cleveland Clinic Health System is pleased to be an equal employment employer: Women / Minorities / Veterans / Individuals with Disabilities
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