Cleveland Clinic • Cleveland, OH 44101
Job #2672992600
Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position will be located at the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, Nevada. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.
LINE-1 retrotransposons and endogenous retroviruses comprise a large portion of the human genome, and their upregulation can lead to induction of innate immune signaling pathways. Our objective is to understand how genome organizing proteins regulate this signaling, with the ultimate goal of identifying new pathways that can be targeted to promote cancer cell death and/or prevent autoinflammatory disease pathogenesis. Our lab is R01 funded, we have been very successful in obtaining federal and private, independent funding for postdocs, and we are excited to add passionate, motivated and creative scientists to our group.
Principal Investigator: Michelle Longworth, PhD
Lerner Research Institute Department: Inflammation & Immunity
Lab Research Topics:
Innate immunity
Endogenous retroviruses
Retrotransposons
Chromatin and epigenetics
Promotion of cancer cell death
For more information about the lab's research, please visit: ~~~/ or contact Dr. Longworth at ~~~ .
Job Responsibilities :
Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
Designing and conducting experiments; analyzing results
Writing scientific manuscripts
Writing fellowships
Attending national and international scientific conferences
Education:
PhD or MD/PhD required
MD with relevant laboratory experience may substitute for PhD
Languages:
Work Experience:
Previous experience in a research or academic setting. Graduate student experience meets this requirement.
Scientific writing experience
Additional Preferred Qualities:
Experience with any of the following:
Retrotransposable elements
Innate immune signaling
CUT&RUN, RNA-seq, scRNA-seq, chromatin confirmation capture techniques
CRISPR/ Cas9
Physical Requirements:
Ability to perform work in a stationary position for extended periods
Ability to operate a computer and other office equipment
Ability to communicate and exchange accurate information
Ability to distinguish color
Manual dexterity to handle specimens and repair equipment
Ability to lift and transport equipment or specimens weighing up to 20 pounds
May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.
Personal Protective Equipment:
Preferred Application Materials:
CV
Short description of thesis work (1-2 paragraphs)
List of 3 references
All application materials should be submitted directly via email to Michelle Longworth at ~~~ .
Keywords: Postdoc, Research, LRI, Immunology, Cancer, Virus, Retrovirus, Epigenetics, Chromatin, Innate immunity, Signaling
Pay Range
Minimum hourly: $0.01
Maximum hourly: $333,340.26
The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement.
Cleveland Clinic Health System is pleased to be an equal employment employer: Women / Minorities / Veterans / Individuals with Disabilities
Cleveland Clinic • Cleveland, OH 44101 • Today
Cleveland Clinic • Cleveland, OH 44101 • Today
Cleveland Clinic • Cleveland, OH 44101 • Today
Cleveland Clinic • Cleveland, OH 44101 • Today
Cleveland Clinic • Cleveland, OH 44195 • 7 Days Ago
Vaco • Cleveland, OH 44101 • 12 Days Ago
Case Western Reserve University • Cleveland, OH 44106 • Apr 19
Cleveland Research Company • Cleveland, OH 44101 • 3 Days Ago